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Peganum harmala: Phytochemistry, Traditional Uses, and Biological Activities

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Biodiversity, Conservation and Sustainability in Asia

Abstract

Peganum harmala is an important medicinal plant, distributed in semiarid rangelands. We investigated the ethnopharmacological knowledge of this medicinal plant together with its botanical characterization and distribution, as well as critical assessment of the phytochemical features and biological activities. This species has been used in traditional medicine from decades. Phytochemical studies on the aerial parts and seeds of the plant have shown that they are rich in alkaloids, essential oils, fatty acids, flavonoids, and anthraquinones. Various parts of this plant including its seeds, bark, and root are highly reputed in the traditional medicine for the treatment of a variety of human ailments, for instance lumbago, asthma, colic, jaundice, and as a stimulant emmenagogue. The fruits are used as analgesic and antiseptic in folk medicine. Reports on the biological activities of the plant are mainly on its alkaloids which have been proven to possess many biological activities.

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Authors and Affiliations

  1. Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan

    N. Z. Mamadalieva

  2. Faculty of Pharmacy, Ain Shams University, Cairo, Egypt

    M. L. Ashour

  3. Medicinal Plants Program, Stockbridge School of Agriculture, University of Massachusetts, Amherst, MA, USA

    N. A. Mamedov

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  1. N. Z. Mamadalieva
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  2. M. L. Ashour
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  3. N. A. Mamedov
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Editors and Affiliations

  1. Department of Botany and Center for Environmental Studies, Ege University, Izmir, Türkiye

    Münir Öztürk

  2. Department of Plant Sciences, Quaid-i-Azam University, Islamabad, Pakistan

    Shujaul Mulk Khan

  3. Biology Department, Hatay Mustafa Kemal University, Antakya-Hatay, Türkiye

    Volkan Altay

  4. Department of Geography, Balıkesir University, Istanbul, Türkiye

    Recep Efe

  5. Faculty of Biology, National University of Uzbekistan, Tashkent, Uzbekistan

    Dilfuza Egamberdieva

  6. Institute of Botany, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan

    Furkat O. Khassanov

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Mamadalieva, N.Z., Ashour, M.L., Mamedov, N.A. (2022). Peganum harmala: Phytochemistry, Traditional Uses, and Biological Activities. In: Öztürk, M., Khan, S.M., Altay, V., Efe, R., Egamberdieva, D., Khassanov, F.O. (eds) Biodiversity, Conservation and Sustainability in Asia. Springer, Cham. https://doi.org/10.1007/978-3-030-73943-0_40

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